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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAV1 All Species: 15.15
Human Site: T205 Identified Species: 30.3
UniProt: P15498 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15498 NP_005419.2 845 98314 T205 C L R E I Q Q T E E K Y T D T
Chimpanzee Pan troglodytes XP_512321 790 91847 K174 K P L Q R F L K P Q D I E I I
Rhesus Macaque Macaca mulatta XP_001083337 847 97793 E205 A E I K Q T E E K Y T E T L E
Dog Lupus familis XP_542134 845 98413 T205 C L R E I Q Q T E E K Y T D T
Cat Felis silvestris
Mouse Mus musculus P27870 845 98118 T205 C L R E I Q Q T E E K Y T D T
Rat Rattus norvegicus P54100 843 97935 T205 C L R E I Q Q T E E K Y T D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505586 846 97900 E205 L L E I Q E T E A K Y Y K T L
Chicken Gallus gallus NP_996745 846 97797 E205 A E I K Q T E E K Y T E T L E
Frog Xenopus laevis NP_001086991 845 97765 L204 R R C C L Q E L Y Q T E E K Y
Zebra Danio Brachydanio rerio NP_001119865 822 94769 L205 E A K Y T E T L E T I E K Y F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NHV9 793 91337 R222 E Q R D Y V I R E L I D T E S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q45FX5 1007 113536 T236 N E N D L Q N T P T L K R N R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.1 58.9 96.2 N.A. 93.1 92.9 N.A. 50.9 59 71.9 55.6 N.A. 32.6 N.A. 28.7 N.A.
Protein Similarity: 100 93.4 75.8 97.8 N.A. 96.2 96.2 N.A. 69.5 75.1 84.1 72.7 N.A. 52.7 N.A. 46.5 N.A.
P-Site Identity: 100 0 6.6 100 N.A. 100 100 N.A. 13.3 6.6 6.6 6.6 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 13.3 26.6 100 N.A. 100 100 N.A. 26.6 26.6 26.6 20 N.A. 40 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 34 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 0 0 0 0 0 0 9 9 0 34 0 % D
% Glu: 17 25 9 34 0 17 25 25 50 34 0 34 17 9 17 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 9 34 0 9 0 0 0 17 9 0 9 9 % I
% Lys: 9 0 9 17 0 0 0 9 17 9 34 9 17 9 0 % K
% Leu: 9 42 9 0 17 0 9 17 0 9 9 0 0 17 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 9 0 0 0 0 0 0 9 0 % N
% Pro: 0 9 0 0 0 0 0 0 17 0 0 0 0 0 0 % P
% Gln: 0 9 0 9 25 50 34 0 0 17 0 0 0 0 0 % Q
% Arg: 9 9 42 0 9 0 0 9 0 0 0 0 9 0 9 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % S
% Thr: 0 0 0 0 9 17 17 42 0 17 25 0 59 9 34 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 9 17 9 42 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _